Drug-like Properties: Concepts, Structure Design and. . Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of.
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From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case studies, structure-property relationship descriptions,.
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Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to.
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Some drugs induce the synthesis of certain drug-metabolizing enzymes and transporters (e.g., CYP, UDP-glucuronosyltransferases (UGT), P-glycoprotein). They initiate expression.
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Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization 2nd Edition by Li Di (Author), Edward Kerns (Author) 7 ratings See all.
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Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization $140.00 Usually ships within 2.
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Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to.
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Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications...
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Drug-Like-Properties-Concepts-Structure-Design-And 2/34 Downloaded from sfsupport2.solidfire.com on by guest developing new therapeutic entities Information on the.
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Drug-Like Properties: Concept, Structure Design and Methods, From ADME to Toxicity Optimization February 2008 DOI: 10.1016/B978-012369520-8.50003-6 Edition: 1st.
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Drug-Like Properties: Concepts, Structure Design and Methods January 2008 Authors: E.H. Kerns Li Di Pfizer Request full-text Abstract Of the thousands of novel.
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Pharmaceutical profiling assays provide an early assessment of drug-like properties, such as solubility, permeability, metabolism, stability and drug-drug interactions, to alert project teams.
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Drug-like properties, such as solubility, permeability, metabolic stability and transporter effects are of critical importance for the success of drug candidates. They affect oral bioavailability,.
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The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as.
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From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case.
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